American activist and playwright Larry Kramer
Credit: David Shankbone (licensed under CC BY 3.0)

The American playwright and AIDS activist Larry Kramer died on Wednesday, May 27, 2020, at the age of 84. (AIDS is the final, life-threatening stages of infection with the human immunodeficiency virus [HIV]). Kramer became known as a fiery advocate (supporter) of public health and gay rights. His advocacy helped not only to further the study and treatment of HIV/AIDS but also to inspire other aggressive public health efforts.

Laurence David Kramer was born on June 25, 1935, in Bridgeport, Connecticut. In 1957, he earned a bachelor of arts degree in English from Yale University. He then entered the motion-picture industry, variously working as screenwriter, story editor, and producer.

In 1981, Kramer cofounded Gay Men’s Health Crisis (GMHC), the first HIV service organization. The organization was created in response to the lack of government action to fight the disease. In 1987, Kramer founded ACT UP (AIDS Coalition to Unleash Power). The organization performed disruptive acts to gain the attention of public officials, scientists, and religious leaders. For instance, the group surrounded St. Patrick’s Cathedral in New York City.

One of the officials with whom Kramer tussled was the American epidemiologist Anthony Fauci. Kramer accused Fauci of having no sense of urgency in studying or treating HIV/AIDS. (In January 2020, Fauci became a lead member of the White House Coronavirus Task Force.) The two later became friends, and Fauci acknowledged the role Kramer had played in drawing attention to the disease.

Kramer is the author of several books, plays, screenplays and essays. His autobiographical play “The Normal Heart” opened in 1985. It explores the rise of the HIV/AIDS crisis in New York City during the early 1980’s. Another autobiographical play, “The Destiny of Me,” was first performed in 1992. The play follows Ned Weeks, the main character of “The Normal Heart.” Kramer wrote a screenplay for the English writer D.H. Lawrence’s novel Women in Love. The film was released in 1969. Kramer received an Academy Award nomination for his screenplay.

Athena, mascot for the SK Wyverns of the Korea Baseball Organization, entertains the only lively member of the crowd during a game at Happy Dream Ballpark, in Incheon, on May 5, 2020. The “fan” is a stadium worker, and the spectators have been replaced by cardboard placards. Live audiences were banned from attending as a result of social distancing measures undertaken to fight a pandemic of the coronavirus disease COVID-19.
Photo credit: © Chung Sung-Jun/Getty Images

The Korea Baseball Organization (KBO) threw out the first pitch of its 2020 regular season on Tuesday, May 5. To much of the rest of the world, the Korean league is known mainly as a source of pitching prospects for Major League Baseball (MLB) and as a place for foreign players to work on their swings. But, with most major sporting leagues shut down due to the ongoing COVID-19 pandemic, the KBO hoped to introduce fans around the world to their version of the pastime.

The Korean league includes 10 teams: the Kiwoom Heroes, LG Twins, Doosan Bears, SK Wyverns, KT Wiz, NC Dinos, Samsung Lions, Lotte Giants, Kia Tigers, and Hanwha Eagles. The regular season consists of 144 games, with each team playing the others 16 times. The top five teams make the playoffs, with the top-ranked team receiving an automatic berth in the seven-game championship series. Each line-up includes a designated hitter, similar to the rule used in MLB’s American League. Unlike MLB games, KBO games can end in ties.

Major league sports around the world have been largely shut down due to social distancing measures undertaken to prevent the spread of the coronavirus disease COVID-19. In the United States, the National Basketball Association became the first major sports organization to suspend play, on March 11. MLB quickly followed, suspending and ultimately cancelling its spring training.

South Korea was able to open its baseball season at only a slight delay, thanks in part to the nation’s aggressive, coordinated response to the COVID-19 outbreak. However, the game will look a little different this year. Everyone but the players is required to wear face masks, and fans, barred from the stadium, have been in some places replaced by cardboard placards.

North American fans who want to check out the action will have to become night owls—due to the time difference, live broadcasts begin in the early morning hours in the United States. But those who stay up late, get up early, or record the game may be rewarded with an earful of a uniquely Korean baseball innovation—cheer songs. Unlike MLB players, who often pick the music played as they step to the plate, Korean players have their own unique theme songs, perhaps unsurprising for a country whose thriving pop music industry gave the world such K-pop (Korean pop music) acts as PSY, BTS, and Blackpink.

American immunologist Anthony Fauci
Photo credit: NIAID

You may have seen Dr. Anthony Fauci featured at press conferences as a member of the White House Coronavirus Task Force, assembled to fight a pandemic (global outbreak) of the coronavirus disease COVID-19. In many ways, Fauci has become the face of efforts to stop the deadly disease in the United States, especially the practice of social distancing. But, how much do you know about Dr. Fauci?

Fauci (pronounced FOW chee), an American immunologist, has served as the director of the National Institute of Allergy and Infectious Diseases (NIAID) since 1984. An immunologist is a scientist who studies the body’s defenses against disease. The NIAID is part of the National Institutes of Health (NIH), an agency of the United States government.

Anthony Stephen Fauci was born on Dec. 24, 1940, in the Brooklyn borough (district) of New York City. He earned a bachelor’s degree at the College of the Holy Cross in Worcester, Massachusetts, in 1962. In 1966, Fauci earned a doctor of medicine degree from Cornell University Medical College in New York City. In 1968, Fauci joined the NIAID’s Laboratory of Clinical Investigation. In 1974, he became head of the Clinical Physiology Section, and he was named chief of the Laboratory of Immunoregulation in 1980. Immunoregulation is the control of immune responses.

As director of the NIAID, Fauci has advised multiple U.S. presidents and led efforts to combat such emerging diseases as the human immunodeficiency virus (HIV, the virus that causes AIDS), SARS, the swine flu, MERS, the Ebola virus, and COVID-19. In 2008, President George W. Bush awarded Fauci the Presidential Medal of Freedom for his efforts in fighting HIV and AIDS. The medal is the highest civilian honor awarded by the president of the United States.

April 8, 2020

Today, April 8, Behind the Headlines was originally scheduled to cover this year’s National Collegiate Athletic Association (NCAA) basketball championships in the United States. However, the men’s and women’s NCAA tournaments were canceled in March because of the ongoing COVID-19 pandemic. The tournaments were not alone: nearly all sports leagues and sporting events have been suspended or canceled because of COVID-19, putting sports on hold in all corners of the globe. COVID-19 is a pneumonia-like disease caused by a coronavirus, a type of virus that also causes the common cold and other diseases of the upper respiratory system. To date, COVID-19 has killed more than 80,000 people among nearly 1.5 million confirmed cases.

Dodger Stadium sits empty in Los Angeles, California. Baseball stadiums, usually teeming with people at this time of year, are going unused throughout the world as leagues have been suspended or canceled because of the COVID-19 pandemic. Credit: John McCoy/Getty Images

All collegiate and high schools sports in the United States were suspended or canceled because of COVID-19 (the schools were then closed), and Little League Baseball, too, had to put off the start of its season. In professional sports, Major League Baseball, which had begun its annual spring training, canceled all exhibition games on March 12 and indefinitely delayed the start of the regular season. Minor League Baseball shut down, as did baseball leagues in Japan, Mexico, South Korea, and other countries. The National Basketball Association suspended its season on March 11, and basketball leagues in other countries were also shut down. The recently launched XFL football league suspended its first season on March 12, and the fledgling Basketball Africa League also lost its inaugural season, which had been scheduled to start on March 13.

The COVID-19 pandemic forced the postponement of the 2020 Summer Olympic Games in Tokyo until 2021. Credit: Pakpoom Phummee/Shutterstock

Major League Soccer and the National Hockey League suspended their seasons in March, and other hockey and soccer leagues around the world were forced to do the same. Rugby and cricket leagues and tournaments were suspended, as were the upcoming Masters Tournament, PGA Championship, U.S. Open, and British Open golf competitions. In tennis, Wimbledon was canceled for the first time since World War II (1939-1945), and the French Open was postponed. The Kentucky Derby horse race and the Indianapolis 500 auto race were postponed, and the Monaco Gran Prix auto race was canceled. (All three races are usually run in May.) Marathons around the world have been canceled or postponed, and athletes of all types will have to wait for the Summer Olympic Games in Tokyo, which were postponed a year until July 2021.

This illustration of Coronavirus Disease 2019 (COVID-19) shows the spikes on the outer surface of the virus that appear as a corona, giving the virus its name. Credit: Centers for Disease Control and Prevention (CDC)

Early in the COVID-19 pandemic, a number of sports continued to be played without fans in attendance, but fears for the safety of athletes quickly led to the canceling of the competitions themselves. Suspended and postponed sports leagues and events have issued optimistic timelines about when they will resume or take place. All timelines, however, depend on the containment or continued spread of COVID-19.

The sports cancellations are part of social distancing, also known as physical distancing, an effort to slow or stop the spread of a contagious disease by limiting contact between people. Social distancing is most effective against illnesses that can be transmitted by coughing or sneezing, direct or indirect physical contact, or through the air. Typical social distancing measures call for the closing of such public places as sports arenas, schools, restaurants, museums, and many offices and stores. They may also call for people to maintain a distance of around 6 feet (2 meters) between them in public places.

February 24, 2020

Last week, on February 19, the Wuhan coronavirus epidemic claimed its 2,000th victim. First recognized in human beings in the Chinese city of Wuhan in December 2019, the coronavirus has since spread steadily and touched nearly all parts of the world. Wuhan coronavirus is an informal name for a respiratory disease named Coronavirus Disease 2019 (COVID-19). Coronaviruses are one of many virus types that cause the common cold and other diseases of the upper respiratory system. The COVID-19 is a pneumonia-like disease. Its symptoms include breathing difficulties, coughing, and fever. It is a contagious disease, and the symptoms can be fatal in a small percentage of cases.

This illustration of Coronavirus Disease 2019 (COVID-19) shows the spikes on the outer surface of the virus that appear as a corona, giving the virus its name. Credit: Centers for Disease Control and Prevention (CDC)

On Jan. 30, 2020, when the disease had caused 170 deaths in some 8,000 confirmed cases, the World Health Organization (WHO) declared the virus outbreak to be a public health emergency of international concern. The WHO recommended urgent containment measures as the number of cases and deaths continued to climb. By mid-February, more than 40,000 cases of the virus had been confirmed. The disease was given the temporary name 2019-nCoV, for novel (new) coronavirus of 2019. It was later officially named COVID-19. The virus that causes the disease was named SARS-CoV-2.

January 20, 2020

Yesterday, January 19, was the 100th anniversary of the founding of the American Civil Liberties Union (ACLU), a nonpartisan organization devoted to defending the rights and freedoms of people in the United States. The ACLU works mainly by providing lawyers and legal advice for individuals and groups in local, state, and federal courts. ACLU officials also testify before state and federal legislative committees, advise government officials, and conduct educational programs. The chief goal of the ACLU is to protect the fundamental rights of individuals as described in the Constitution of the United States.

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ACLU logo. Credit: © ACLU

In 1917, a group of social activists founded the National Civil Liberties Bureau (NCLB) to support the Bill of Rights. The NCLB was led by Roger Baldwin, a social worker and civil rights champion, and Crystal Eastman, a lawyer and leader in the woman suffrage and equal rights movements. The NCLB became the ACLU in 1920, the same year that women in the United States won the right to vote.

The ACLU has defended the constitutional rights of a wide range of individuals and groups. It played an important part in Supreme Court rulings that guaranteed legal aid to poor people. The group has supported fair treatment of conscientious objectors, people whose conscience does not allow them to take part in war. The ACLU urged the desegregation of schools and promoted the African American civil rights movement. One of the current goals of the ACLU is the abolition of capital punishment. The group also calls for further restrictions on government investigative agencies and for stricter separation of church and state. In addition, it seeks greater protection for the rights of immigrants who enter the United States without the required papers and for the rights of lesbian, gay, bisexual, and transgender people.

The ACLU has played a significant part in some of the landmark civil rights cases in American history. The ACLU backed both biology teacher John Scopes and attorney Clarence Darrow in the Scopes trial of 1925, which challenged a Tennessee law that outlawed the teaching of evolution in schools. During World War II (1939-1945), the ACLU fought against the internment of Japanese Americans. In 1954, the ACLU joined with the National Association for the Advancement of Colored People (NAACP) to challenge racial segregation in public schools. The ACLU defended individual freedom of speech in 1968 and women’s reproductive rights in 1973. In 1978, the ACLU famously defended the free speech of an American Nazi group who wanted to march in Illinois. The ACLU believes that constitutional rights apply to everyone regardless of individual ideology.

January 13, 2020

Earth has been a particularly dangerous place in recent weeks. Airplane crashes, military clashes, terror attacks, and political unrest have taken a toll on human life and happiness lately, but it is a series of natural disasters that has caused the most trouble. A typhoon ravaged the Philippines, deadly flash floods hit Indonesia, bushfires continued to rage in Australia, a measles epidemic continued to kill in the Democratic Republic of the Congo, and a series of earthquakes rattled Puerto Rico.

Firefighters confront a bushfire near the Blue Mountains town of Bilpin, New South Wales, on Dec. 19, 2019. Credit: © 1234rf/Shutterstock

On Christmas Eve and Christmas Day Typhoon Phanfone (also called Ursula) struck the Philippines, producing high winds and flooding that killed 105 people in the Visayan Island provinces of Biliran, Capiz, Iloilo, and Leyte. Phanfone was a Category 2 storm (moderate strength) with sustained winds of more than 90 miles (150 kilometers) per hour. Storm surges and deadly flash floods hit communities just as families were gathering to celebrate the Christmas holiday. Thousands of homes were damaged or destroyed.

On New Year’s Day in Indonesia, abnormally heavy monsoon rains caused flash floods that killed 66 people and displaced hundreds of thousands of others in Jakarta, the capital. Some 14.5 inches (37 centimeters) of rain fell on New Year’s Eve, causing the Ciliwung and Cisadane rivers to overflow. Floodwaters submerged more than 150 neighborhoods and caused landslides in the Bogor and Depok districts on the outskirts of Jakarta. Flood water levels in some areas peaked at more than 13 feet (4 meters). Electric power was cut off, and closed schools and government buildings were converted into emergency shelters.

On January 7, the World Health Organization announced the 6,000th death from measles in the Democratic Republic of the Congo (DRC) since an epidemic began there in 2019. More than 300,000 suspected measles cases have been reported in the DRC—a nation also troubled by recent terror attacks. The epidemic has continued and grown because of low vaccination coverage, malnutrition, weak public health systems, outbreaks of other epidemic-prone diseases (such as Ebola), and the difficulty of getting health care to people in remote areas.

In Puerto Rico, after several smaller earthquakes, a 6.4-magnitude temblor struck the southwestern part of the island on January 7. The earthquake, the strongest to hit Puerto Rico in more than 100 years, killed one person, toppled hundreds of structures, and forced a state of emergency. Many people lost their homes, the island briefly lost electric power, and schools and public offices were closed. In the 10 days before the 6.4-magnitude earthquake, the United States Geological Survey recorded hundreds of temblors in Puerto Rico—including 10 of 4-magnitude or greater.

A number of major bushfires have lately devastated southeastern Australia. Since September, the wild fires—mostly in New South Wales, Queensland, and Victoria—have burned more than 25.5 million acres (10.3 million hectares), an area the size of South Korea. The bushfires have destroyed more than 2,100 homes and killed 27 people and hundreds of millions of animals. On January 8, the Australian government ordered the mass slaughter of thousands of wild camels and horses that have invaded rural towns looking for water. Many people are without electric power and telecommunications in Australia’s southeast, and some were without drinking water and other supplies. Smoke has obscured the city skies of Canberra, Melbourne, and Sydney. The bushfires followed a three-year drought that experts link to climate change.

October 11, 2019

Every year in the first week of October, the Nobel Foundation in Sweden awards Nobel Prizes to artists, economists, scientists, and peace workers who—in keeping with the vision of the Swedish chemist and industrialist Alfred Nobel—have conferred the greatest benefit to humankind. Today, World Book looks at the first three prizes, in the scientific categories of physiology or medicine, physics, and chemistry.

Nobel Prize medal (Credit: Nobel Foundation)

On Monday, October 7, 2019, the Nobel Prize in physiology or medicine was given jointly to the scientists William G. Kaelin, Jr., Sir Peter J. Ratcliffe, and Gregg L. Semenza for their work showing how cells adapt to the changing availability of oxygen. Kaelin, Ratcliffe, and Semenza identified the molecular machinery that allows cells to respond to changes in oxygen levels. Their discoveries offer promising new strategies in the treatment of such diseases and maladies as anemia, cancer, heart attacks, and strokes.

William G. Kaelin, Jr., was born in New York and is a professor of medicine at the Dana-Farber Cancer Institute in Boston and at the Brigham and Women’s Hospital at Harvard Medical School. Peter J. Ratcliffe of the United Kingdom is the director of clinical research at the Francis Crick Institute in London and director of the Target Discovery Institute at the University of Oxford. Gregg L. Semenza, also from New York, is a professor of genetic medicine at Johns Hopkins University in Baltimore, Maryland.

On Tuesday, October 8, the Nobel Foundation announced the prize for physics had been awarded to the Canadian-American cosmologist James Peebles and to the Swiss scientists Michel Mayor and Didier Queloz for their work on explaining the evolution of the universe and for discovering distant exoplanets (planets beyond our solar system). Among other things, Peebles theorized how matter in the young universe swirled into galaxies. In 1995, Mayor and Queloz discovered an exoplanet orbiting a star elsewhere in our home galaxy, the Milky Way, enhancing the study of planetary systems beyond our own that could support life.

James Peebles is the Albert Einstein professor of science at Princeton University in New Jersey. Michel Mayor is an astrophysicist and professor emeritus of astronomy at the University of Geneva. Didier Queloz is a professor of physics at the Cavendish Laboratory at Cambridge University, and at the University of Geneva.

On Wednesday, October 9, the Nobel Foundation announced that John B. Goodenough of the United States, M. Stanley Whittingham of the United Kingdom, and Akira Yoshino of Japan would share the prize for chemistry for developing and refining rechargeable lithium-ion batteries. The lightweight, rechargeable, and powerful batteries are used in everything from mobile phones to laptop computers and electric vehicles. They can also store great amounts of energy from solar and wind power, further enabling the possibility of a fossil fuel-free future.

At 97 years old, John B. Goodenough is the oldest ever recipient of the Nobel Prize. He is currently the Virginia H. Cockrell Chair in Engineering at the University of Texas at Austin. M. Stanley Whittingham is a distinguished professor at Binghamton University, State University of New York. Akira Yoshino is an honorary fellow at Tokyo’s Asahi Kasei Corporation and a professor at Meijo University in Nagoya, Japan.

August 12, 2019

Late last month, on Sunday, July 28, a southern white rhinoceros calf was born at the San Diego Zoo Safari Park in southern California. The baby rhino, named Edward, marks the first instance of a successful artificial insemination (pregnancy induced by other than natural means) birth of a southern white rhino in North America. Artificial insemination of southern white rhinos, which were once endangered, has rarely been successful. Just two other southern white rhinos have been born this way prior to Edward’s joyful appearance. But baby Edward may soon have company. A second artificially inseminated southern white rhino is due to give birth at the safari park later this year.

One-day old Edward shelters beneath his mother, Victoria, at the Nikita Kahn Rhino Rescue Center at the San Diego Zoo Safari Park on July 29, 2019. Credit: © San Diego Zoo

Edward’s mother, Victoria, was artificially inseminated on March 22, 2018, following hormone-induced ovulation. White rhino gestation (the period of pregnancy) is normally around 485 days—but Victoria carried her calf for 493 days. That’s more than 16 months! The San Diego Zoo Safari Park, a center for the preservation and display of endangered species, has naturally bred southern white rhinos before. But the artificial insemination and Edward’s successful birth represented an important step in increasing white rhino as well as other rhinoceros populations that are critically endangered—particularly the northern white rhino, a subspecies of the southern white rhino.

Only two northern white rhinos remain on Earth, and both are female and beyond breeding age. The last male died in March 2018. Scientists have access to frozen reproductive material of the northern white rhino, however, and they hope to use artificial insemination or in vitro fertilization (IVF) to allow a southern white rhino to act as a surrogate mother. In IVF, an embryo is created in a laboratory and then transferred to a surrogate mother. Scientists hope to achieve a northern white rhino birth within the next 10 years. Without some form of assisted reproduction, the animals will soon be extinct.

Southern white rhinos, too, once stood on the brink of extinction. In the early 1900′s, overhunting and habitat loss had reduced Africa’s southern white rhino population to fewer than 50 animals. Protections and conservation measures allowed the population to rebound, however, and today thousands of animals live both in the wild and in parks and zoos around the world.

The white rhino is the largest of all rhinoceroses. It stands about 5 to 6 feet (1.5 to 1.8 meters) tall. In some cases, it may be over 6 feet (1.8 meters) tall and 15 feet (4.6 meters) long. It weighs up to 4 tons (3.6 metric tons). The animals face grave threats from habitat loss and poachers, who illegally kill rhinoceroses and sell their horns and skin. In some Asian traditions, the powdered horn of the rhinoceros is believed to have healing qualities. Rhinoceros skin, blood, and urine are also sometimes used in traditional medicine.

May 8, 2019

Measles is making a comeback. The highly contagious disease is characterized by the spotty pink rash it causes over the body. Once rare, measles has come roaring back in the United States, as more than 750 cases were officially recorded in the first four months of 2019. That number is more than twice the amount of U.S. cases typically recorded in a full year. The new measles cases were primarily recorded in large outbreaks in the states of New York and Washington, but the disease has also appeared in 21 other states.

A health worker gives a measles vaccine to a young girl in Peshawar, Pakistan. Credit: © Asianet-Pakistan/Shutterstock

Measles chiefly strikes young children, but it is increasingly affecting adolescents and young adults. People who have the disease pass the virus by coughing and sneezing. People can spread the disease long before they realize they are ill. Three to five days after the first symptoms appear, faint pink spots break out over the body. Few people in the United States die of measles. But the disease is dangerous to those with a weakened immune system, and measles kills many undernourished children in other countries.

A child with measles shows the characteristic pink rash that spreads over the body. Credit: © Lowell Georgia, Photo Researchers

Public health experts are dismayed that measles has regained a foothold in the United States, where it was once eradicated. In 2000, the U.S. Centers for Disease Control and Prevention (CDC) announced that measles had been completely eliminated. This was an important public health achievement made possible by the widespread use of the highly effective measles vaccine. Of course, that did not mean that measles was completely gone. CDC officials still recorded a number of cases brought in from travelers—mostly from parts of Asia and Europe where measles is less well controlled. But, until recently, measles transmission in the United States had ended.

In recent years, however, a misinformed yet highly visible anti-vaccination (anti-vaxx for short) movement has led to fewer vaccinations, which has in turn led to the current measles outbreak. Anti-vaxx activists in the United States have launched a coordinated effort to convince parents not to vaccinate their children. They falsely claim that childhood vaccinations can cause a variety of health complications, autism, or even death. This disinformation is spread through websites, Facebook, and other social media. Medical professionals point out that anti-vaxx claims are often misleading and lack any credible or relevant evidence.

The anti-vaxx movement has spearheaded efforts to allow parents to opt out of mandatory vaccinations previously require to enroll their children in public schools. The latest measles outbreak is spread primarily though such unvaccinated students, who expose other children to measles and other preventable diseases, such as whooping cough.

Unvaccinated people, including those who may have a weakened immune system from chemotherapy, can be protected from measles through herd immunity. This term describes a population protected from a disease because high rates of vaccination make it impossible for the virus to spread. Although the measles virus can remain infectious for two or more hours outside the human body, the virus ultimately requires a human host to reproduce. If enough people in a population are vaccinated, the cycle of transmission is disrupted, and the virus will become extinct.

However, herd immunity does not work unless a great majority of the population is vaccinated. To achieve herd immunity for measles, at least 90 to 95 percent of the population needs to be vaccinated. In the past, this was achieved through mandatory vaccinations for school children. In recent years, however, increasing numbers of parents have requested vaccine exemptions for their children on ethical or religious grounds. Many states, cities, and school districts are now reconsidering allowing such exemptions.