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Archive for the ‘Medicine’ Category

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Black History Month: Henrietta Lacks

Wednesday, February 1st, 2023

 

Henrietta Lacks' cancer cells, called HeLa, are used around the world for medical experiments. Credit: © Pictorial Press Ltd, Alamy Images

Henrietta Lacks’ cancer cells, called HeLa, are used around the world for medical experiments.
Credit: © Pictorial Press Ltd, Alamy Images

February is Black History Month, an annual observance of the achievements and culture of Black Americans. This month, Behind the Headlines will feature Black pioneers in a variety of areas.

A mother and a medical marvel with a lasting legacy, Henrietta Lacks has saved nearly 10 million lives. Lacks was an African American woman born in Roanoke, Virginia, on August 1, 1920. Lacks unknowingly became a donor of a line of cells widely used in medical research. Those cells, known as HeLa cells, became one of the most important advances in medical science. HeLa stands for Henrietta Lacks. Lacks only lived 31 years, but her cells are still alive today.

Lacks was born Loretta Pleasant. She later changed her name to Henrietta and married David Lacks in 1941. The couple moved to Baltimore, Maryland, in the 1940’s. In 1951, she was diagnosed with cervical cancer at the Johns Hopkins Hospital. She died on October 4 of that year, leaving behind her five children. Before her death, doctors removed a sample of cancer cells during a medical examination. The sample was taken without her knowledge.

Scientists at Johns Hopkins University used the sample to establish the HeLa cell culture. A cell culture is a population of cells grown under controlled conditions for research. The usefulness of cell cultures is often limited because the cells die after a certain number of divisions. However, the HeLa cells divided indefinitely without dying.

HeLa cells grow faster than other cell cultures. They survive shipment by mail, enabling them to be sent to laboratories around the world. The unique qualities of HeLa cells led to many scientific discoveries and a greater understanding of biological processes. One of the first uses of HeLa cells was to test the safety and effectiveness of a vaccine for the disease polio. HeLa cells have also contributed to treatments for Parkinson’s, HIV, and AIDS, as well as vaccines for the flu, HPV, and COVID-19. Her cells have been used in nearly 75,000 studies.

The World Health Organization honored Henrietta Lacks in 2021. The city of Roanoke, Virginia, is replacing a statue of confederate general Robert E. Lee with a bronze statue of Lacks. Nearly 72 years after her death, Lacks will be memorialized in her hometown for years to come. Author Rebecca Skloot wrote about Henrietta’s life and her medical contribution in The Immortal Life of Henrietta Lacks released in 2010. The story was adapted into a movie in 2017 starring Oprah Winfrey.

HeLa cells were also used to produce the first cellular clones. Cellular clones are a group of cells descended from a single cell. They are genetically identical, enabling scientists to study entire populations of cells with a particular genetic trait.

HeLa cells remain an essential tool in laboratories throughout the world. They have been used to develop drugs and other therapies worth billions of dollars. However, Henrietta Lacks and her family received no compensation for the use of her cells. In medical ethics, her case is often cited as a classic example of failure to obtain informed consent from a tissue donor. Informed consent means that participants fully understand and accept the known risks and possible benefits of a medical procedure. Today, researchers regularly obtain consent from patients before taking tissue samples.

In 2013, the United States National Institutes of Health (NIH), a government agency that conducts and supports a broad range of biomedical research, made a historic agreement with the surviving family of Henrietta Lacks. NIH researchers must now obtain permission from a special review panel before they can view and use detailed genetic information of HeLa cells. Members of the Lacks family are included on the review panel. NIH also requested that researchers studying HeLa cells include an acknowledgment to the Lacks family when the research is published.

Tags: african american history, black history month, black women, cells, culture, national institutes of health, world health organization
Posted in Current Events, Medicine, Science | Comments Off

World AIDS Day

Thursday, December 1st, 2022
AIDS viruses reproduce in CD4 cells and circulate in the blood. In this electron micrograph of a white blood cell, AIDS viruses can be seen as the small white dots covering the cell's surface. Credit: Centers for Disease Control and Prevention

AIDS viruses reproduce in CD4 cells and circulate in the blood. In this electron micrograph of a white blood cell, AIDS viruses can be seen as the small white dots covering the cell’s surface.
Credit: Centers for Disease Control and Prevention

Today, December 1, 2022, is World AIDS Day. AIDS is the final, life-threatening stages of infection with the human immunodeficiency virus (HIV). HIV damages the immune system, the human body’s most important defense against disease. AIDS stands for acquired immunodeficiency syndrome or acquired immune deficiency syndrome. On this day, we honor over 40 million people who have lost their lives to AIDS and look ahead to ending the AIDS pandemic through research, healthcare, and community support. The World Health Organization reported that 38.4 million people were living with HIV across the globe at the end of 2021.

AIDS is a relatively new life-threatening disease. HIV is spread through sexual intercourse with an infected person or exposure to blood from an infected person, many times through shared needles used to inject drugs. At first, it mainly affected young adults. In the public imagination, the disease soon became associated with risky sexual behavior and with drug abuse. For all these reasons, efforts to address AIDS or to prevent the spread of HIV have at times faced unique social challenges. An infected pregnant woman can transmit HIV to her unborn child before and during the delivery, even if the woman shows no symptoms. An HIV-infected mother may also pass HIV to her baby through breast-feeding.

Since 1986, the international health community has worked to coordinate the global fight against HIV and AIDS. The World Health Organization’s Global AIDS Programme formed the Joint United Nations Programme on HIV/AIDS (UNAIDS) in 1996. Since that time, UNAIDS has worked with other international partners to coordinate the global fight against HIV and AIDS. UNAIDS reported recently that one obstacle to ending AIDS around the world is gender inequality. Many girls and women live with HIV and AIDS without treatment and education to prevent infection. They report that in countries where girls do not receive an education, the rates of HIV infection are higher. UNAIDS also stated that in countries where same-sex relationships are criminalized the probability of infection is increased.

Many individuals and organizations have worked to increase public awareness of AIDS. The most active organizations include community-based groups and the American Red Cross. They hope that greater awareness will generate more compassion and support for people living with AIDS. They also hope to ensure adequate funding for HIV prevention, treatment, and research. One prominent project bringing attention to the crisis is the AIDS Memorial Quilt. Begun by the NAMES Project Foundation in 1987, the quilt consists of thousands of individually designed panels. The panels memorialize people who died of AIDS. The quilt has been displayed throughout the world.

Poor understanding of HIV has at times stoked public fears, leading many people with the virus to suffer unjustly. Some of the infected have lost or been denied jobs or housing. Others have been denied medical care and health insurance. Many children with AIDS were initially barred from attending school or playing on sports teams. To prevent discrimination, people with HIV and AIDS are often included under laws protecting the rights of people with disabilities. The United States government and some states have also strengthened laws safeguarding the confidentiality of medical records relating to HIV infection and AIDS.

Preventing discrimination against people with HIV is not only just—it also protects public health. When people can live without fear of discrimination, they are more likely to seek counseling and treatment. In many cases, such measures lead to earlier diagnosis and a reduction in risky behavior.

AIDS was first identified as a disease by physicians in California and in New York City, New York, in 1981. Doctors recognized the condition as something new because all the patients were previously healthy, young gay men. They sought medical care because they were suffering from otherwise rare forms of cancer and pneumonia. In 1982, the disease was named AIDS. Scientists soon determined that AIDS occurred when the immune system became damaged. They also learned that the agent that caused the damage was spread through sexual contact, shared drug needles, and infected blood transfusions.

AIDS occurs in every nation. In areas such as Africa south of the Sahara, Southeast Asia, and India, HIV transmission has occurred mostly among heterosexual men and women, particularly young adults and teens. Many developing nations carry enormous burdens of HIV infection. For example, the United Nations reports that in some parts of Africa, the infection rate may reach over 30 percent in some urban areas. The huge number of young adults dying of AIDS in Africa south of the Sahara has decreased overall life expectancy across the continent. A growing number of people have also become infected in countries with increasing drug use, such as Russia, China, and the nations of central Europe.

 

Tags: aids, health, healthcare, hiv, immune system, infection, medicine, pandemic, testing, world aids day, world health organization
Posted in Current Events, Medicine | Comments Off

What is Monkeypox?

Tuesday, May 24th, 2022
An electron microscope shows monkeypox virus particles. Credit: Cynthia S. Goldsmith and Russell Regnery, CDC

An electron microscope shows monkeypox virus particles.
Credit: Cynthia S. Goldsmith and Russell Regnery, CDC

On May 13, 2022, the World Health Organization was notified of two confirmed cases of monkeypox in the United Kingdom. Not the chickenpox, monkeypox! Since then, cases have been detected in Canada, Italy, Portugal, Spain, Sweden, and the United States. Many people are now asking: what is monkeypox and how bad is it?

Monkeypox is a viral disease that affects animals and, in rare cases, human beings. Scientists first isolated and identified the monkeypox virus from laboratory monkeys in 1958. They obtained it from monkeys that had an unusual rash of skin pustules (small bumps filled with fluid). Historically, such pustules were called pox, leading to the name monkeypox. Other animals, including rats, squirrels, and mice, can also carry monkeypox.

People that eat or get bitten by infected animals can catch monkeypox, but the virus does not spread easily from person to person. The disease is uncommon in human beings. The first human case of monkeypox was not recorded until 1970.

Monkeypox occurs naturally among wild animal populations of central and western Africa. Since the 1970’s, it has caused occasional outbreaks of illness among people in the region. In 2003, 71 people in Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin became ill with confirmed or suspected cases of monkeypox. They caught the disease after handling prairie dogs that were purchased at a pet shop in Illinois. Prairie dogs do not naturally carry the monkeypox virus. The animals became infected at the pet shop, where they were housed with a rodent called a Gambian giant rat that carried the virus. An animal dealer had imported the rat from Africa to sell it as a pet.

Several people were hospitalized in the 2003 outbreak, but there were no deaths. Physicians and veterinarians quickly quarantined (isolated) people and animals that might have been exposed to the virus. This action was designed to prevent the disease from spreading to other people, pets, or wild animals. Following the outbreak, the United States Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) banned the importation of rodents from Africa. They also banned the transport and sale of prairie dogs and African rodents within the United States.

Symptoms of the disease develop about two weeks after a person is exposed to the monkeypox virus. Symptoms include fever, headache, muscle pain, backache, and swelling of lymph nodes. Following the fever, a rash appears on the face and other parts of the body. The rash develops into fluid-filled pustules, which dry up and fall off. The illness lasts from two to four weeks. In Africa, from 1 percent to 10 percent of people infected with monkeypox die from the disease.

Physicians suspect monkeypox if a person shows the symptoms and has had contact with an infected person or animal. Laboratory tests are used to detect the monkeypox virus in samples from blood, pustules, or scabs of patients.

People can prevent infection by not handling wild animals that may carry the virus. The monkeypox virus is related to the virus that causes smallpox. Smallpox vaccine can protect against monkeypox when it is given before a person is exposed to the virus. Smallpox vaccination given after exposure to monkeypox may help prevent the disease or make it less severe. However, because the disease is uncommon, health officials do not recommend widespread smallpox vaccination to protect people from monkeypox.

Tags: infection, monkeypox, pox, virus, world health organization
Posted in Current Events, Health, Medicine | Comments Off

National Nurses Week

Friday, May 6th, 2022
A nurse greets a patient with an elbow bump.  Credit: © 2021 Prostock-studio/Shutterstock.

A nurse greets a patient with an elbow bump.
Credit: © 2021 Prostock-studio/Shutterstock.

National nurses week begins today, May 6, 2022. Each year an entire week is dedicated to the hardworking, brave, and caring nurses who take care of sick, injured, and vulnerable patients. If you know or see any nurses this week, make sure to tell them “thank you” for all that they do. The week always ends on May 12, the birthday of Florence Nightingale. Nightingale founded the nursing profession as we know it today.

Born into a wealthy British family in 1820, Nightingale was expected to marry. However, she felt called to help the sick. She led the care of injured soldiers in the Crimean War (1853-1856). From this work, she became a world authority on scientific care of the sick. In 1860, Nightingale used donations of about $222,000 to found the first school of nursing, Nightingale Training School for Nurses at St. Thomas’s Hospital in London. The United States asked Nightingale’s advice for setting up military hospitals during the American Civil War (1861-1865). Nightingale received many honors and became the first woman to be given the British Order of Merit. She died on Aug. 13, 1910.

Nursing is a profession that provides care to the sick, the injured, and other people in need of medical assistance. Nurses perform a wide variety of duties in many settings. Many nurses work in hospitals, outpatient clinics, or other health care facilities. Other nurses work in health insurance companies, research institutions, and pharmaceutical (medicinal drug) companies. Nurses also work in schools, factories, and the armed forces. Nurses may run general health screening or immunization clinics and blood drives.

Patients often get most of their direct health care through nurses. Among their duties, nurses record patient medical histories and symptoms, help perform medical tests, administer treatment and medications, operate medical machinery, and help with follow-up care and rehabilitation. They also provide advice and emotional support to patients and their families.

Nurses educate patients about various medical conditions. They teach patients and their families how to manage illnesses or injuries. They explain home care needs, including diet, nutrition, and exercise programs; physical therapy; and how to take medication. Some nurses work to promote public knowledge about health and health care. They may give public lectures on health and medical topics.

More women serve in the field of nursing than in any other profession except teaching. However, this trend is changing. Until the 1960′s, men made up only 1 percent of professional nurses. By the early 2000′s, men made up more than 10 percent of students enrolled in undergraduate professional nursing programs. Men make up about 6 percent of professional nurses.

Nursing offers satisfaction to those who desire to help others. It also provides a wide range of job opportunities. A capable nurse—especially one with an advanced degree—can generally feel sure of a job. Salaries for nurses are often high compared with those for other professions. A nurse must like people and want to help them. A nurse must also have self-reliance and good judgment. Patience, tact, honesty, responsibility, and the ability to work easily with others are valuable traits. Good health is another requirement.

Nurses have worked tirelessly throughout the COVID-19 pandemic. In 2020, many nurses took care of people sick from COVID-19 and quarantined away from their families and friends to prevent spreading the virus. While nurses always deserve praise and gratitude, throughout the past few years they have been true heroes.

 

Tags: florence nightingale, health, immunization, may, national nurses week, nursing
Posted in Current Events, Medicine | Comments Off

COVID-19: One Year Later

Thursday, March 11th, 2021
L-R) Douglas Emhoff, U.S. Vice President-elect Kamala Harris, Dr. Jill Biden and U.S. President-elect Joe Biden look down the National Mall as lamps are lit  to honor the nearly 400,000 American victims of the coronavirus pandemic at the Lincoln Memorial Reflecting Pool January 19, 2021 in Washington, DC. As the nation's capital has become a fortress city of roadblocks, barricades and 20,000 National Guard troops due to heightened security around Biden's inauguration, 200,000 small flags were installed on the National Mall to honor the nearly 400,000 Americans killed by COVID-19. Credit: © Chip Somodevilla, Getty Images

A candlelit vigil on the National Mall in Washington, D.C., on Jan. 19, 2021, honored the hundreds of thousands of Americans killed by COVID-19.
Credit: © Chip Somodevilla, Getty Images

One year ago, on March 11, 2020, the World Health Organization declared the coronavirus disease COVID-19 a pandemic—that is, a disease that spreads over an extremely wide geographic area. In one year, the deadly respiratory disease has infected nearly 115 million people and killed more than 2.5 million people worldwide.

The first COVID-19 cases occurred in Wuhan, China, near a seafood and live animal market. This fact suggested to scientists that the disease may be zoonotic (spread from animals to people). Researchers proposed that, like the related diseases MERS (Middle East respiratory syndrome) and SARS (severe acute respiratory syndrome), COVID-19 may have its origin in bats. Further analysis of the virus SARS-CoV-2 showed that it had clearly originated in bats. SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2. How the virus crossed over into human beings has not been determined. After the virus entered humans, human-to-human transmission became the chief way in which the disease spread.

As the pandemic progressed, some authorities closed schools and such nonessential businesses as restaurants, movie theaters, and hair salons. Some officials issued stay-at-home orders. The orders forbade people from leaving their homes except for such necessary activities as working at an essential job, buying food, or seeing a doctor.

To pass time over the long year and help stay cheerful while stuck at home, many people turned to baking treats, reading books, and making arts and crafts. For instance, some people recreated famous paintings. Such museums as the Getty Center in Los Angeles, California, provided people with prompts. Then, using household products and costumes buried at the bottom of toy chests, people recreated famous works of art. Emanuel Leutze’s “Washington Crossing the Delaware,” for example, became “Wagon Crossing the Street.” Re-enacting masterpieces was a great way to past the time, while you waited for your treats to bake.

Sandra Lindsay, left, an African American nurse, is injected with the COVID-19 vaccine developed by Pfizer on Dec. 14, 2020, in the Queens borough (section) of New York City. The rollout of the vaccine, the first to be given emergency authorization by the Food and Drug Administration, begins the biggest vaccination effort in U.S. history.  Credit: © Mark Lennihan, Getty Images

Sandra Lindsay, left, a Black nurse, is injected with the COVID-19 vaccine developed by Pfizer on Dec. 14, 2020, in the Queens borough (section) of New York City. The rollout of the vaccine, the first to be given emergency authorization by the Food and Drug Administration, begins the biggest vaccination effort in U.S. history.
Credit: © Mark Lennihan, Getty Images

In December 2020, hope began to arrive in the form of vaccines. Vaccines are special medicines that can help make a person immune to a particular disease. The long-awaited “V-Day,” short for Vaccine Day, arrived in the United States on Monday, Dec. 14, 2020. Sandra Lindsay—a nurse at a hospital in the Queens borough (section) of New York City—was hailed as the first person in the United States to receive an authorized COVID-19 vaccination.

Not everyone who wants a vaccine has been able to get one right away. The first doses were given to healthcare workers. Then, frontline workers (workers likely to encounter the disease) followed, along with people vulnerable to the virus, including the elderly and those with such risk factors as obesity or diabetes.

Since December, nearly 10 percent of the U.S. population has received the vaccine. Tens of thousands more get vaccinated each day, raising hopes that the end of the pandemic is near.

Tags: coronavirus, COVID-19, pandemic, public health, vaccine
Posted in Current Events, Disasters, Health, Medicine, Natural Disasters, Recreation & Sports, Science | Comments Off

Have a Safe and Happy New Year!

Thursday, December 31st, 2020
Credit: © Atstock Productions, Shutterstock

Credit: © Atstock Productions, Shutterstock

Friday, January 1, is New Year’s Day, the first day of the calendar year. People in almost every country celebrate this day as a holiday. The celebrations are both festive and serious. Many people make New Year’s resolutions to break bad habits or to start good ones. Some think about how they have lived during the past year and look forward to the next 12 months.

In a typical year, New Year’s celebrations may include visiting friends and relatives, giving gifts, and attending religious services. Celebrations usually start on New Year’s Eve, December 31. In the United States, many people go to New Year’s Eve parties. Crowds gather in Times Square in New York City, on State Street in Chicago, and in other public places. At midnight, bells ring, sirens sound, firecrackers explode, and everyone shouts, “Happy New Year!”

Of course, 2020 has not been a typical year, and 2021 New Year’s festivities are likely to look a little different. Efforts are being made to prevent the spread of the pandemic (global outbreak) of the coronavirus disease COVID-19. Such efforts often include social distancing, meant to limit contact among people and thus the spread of germs. So, gone are the large crowds in Times Square. In addition, such traditional New Year’s Day celebrations as visiting friends and relatives or attending religious services might be limited to virtual events this year.

Many people may be particularly excited to say good-bye to 2020. The year was largely overshadowed by the pandemic. COVID-19 was first recognized in human beings in Wuhan, China, in late 2019. By January 30, COVID-19 had caused 170 deaths among some 8,000 confirmed cases. The World Health Organization (WHO) declared the outbreak to be a public health emergency of international concern. WHO recommended urgent containment measures as the number of cases and deaths continued to climb. On March 11, WHO declared COVID-19 a pandemic.

As the pandemic progressed, some authorities closed schools and such businesses as restaurants, movie theaters, and barber shops and hair salons. Some officials issued stay-at-home orders. The orders forbade people from leaving their homes except for such necessary activities as working at an essential job, buying food, or seeing a doctor.

As of late December, COVID-19 has caused more than 1.7 million deaths worldwide, and more than 82.1 million cases had been confirmed. More than 185 countries have reported cases of COVID-19.

However, the new year offers hope in the form of vaccines, special medicines that can help make a person immune to a particular disease. The long-awaited V-Day, short for Vaccine Day, arrived in the United States on Monday, December 14, with the beginning of widespread vaccination against COVID-19. The first vaccine doses were given to health care workers. Next in line are frontline workers (workers likely to encounter the disease) and people who are vulnerable to the virus, including the elderly and people with such risk factors as obesity or diabetes. Some of these people have already received the vaccine, but most people may have to wait to be vaccinated until the spring of 2021.

So, it will take some time for things to return to normal. But, here’s wishing you a happier and healthier 2021!

Tags: 2020, 2021, COVID-19, new year's day, new year's eve, vaccines
Posted in Current Events, Disasters, Health, Holidays/Celebrations, Medicine | Comments Off

“V-Day” Arrives in the U.S.

Tuesday, December 15th, 2020
Sandra Lindsay, left, an African American nurse, is injected with the COVID-19 vaccine developed by Pfizer on Dec. 14, 2020, in the Queens borough (section) of New York City. The rollout of the vaccine, the first to be given emergency authorization by the Food and Drug Administration, begins the biggest vaccination effort in U.S. history.  Credit: © Mark Lennihan, Getty Images

Sandra Lindsay, a Black nurse, is injected with the COVID-19 vaccine developed by Pfizer on Dec. 14, 2020, in the Queens borough (section) of New York City. The rollout of the vaccine, the first to be given emergency authorization by the Food and Drug Administration, begins the largest vaccination effort in U.S. history.
Credit: © Mark Lennihan, Getty Images

The long-awaited V-Day, short for Vaccine Day, arrived in the United States on Monday, December 14, with the beginning of widespread vaccination against the coronavirus disease COVID-19. Vaccination involves the administration of special medicines called vaccines, which can help make a person immune to a particular disease. Sandra Lindsay—a nurse at a hospital in the Queens borough (section) of New York City—became the first person in the United States to receive the authorized COVID-19 vaccination. COVID-19 has killed more than 1 million people and infected more than 60 million people around the world. The United States Food and Drug Administration (FDA) granted an emergency use authorization for the vaccine, by the pharmaceutical company Pfizer, on December 11. V-Day provided a moment of hope against the COVID-19 pandemic (worldwide outbreak of disease) even as the U.S. death toll topped 300,000.

The fact that Lindsay—a Black health care worker—was first in line to receive the vaccine is significant. In the United States, COVID-19 has disproportionally affected Black Americans, and medical workers have been on the front line of the fight against the disease. Lindsay said it was important for her to take the vaccine, in part because of the history of unequal and racist treatment of minorities in the medical system. In particular, she mentioned the Tuskegee Syphilis Study, a notorious medical experiment involving Black Americans. Beginning in 1932, medical workers conducted blood tests among 4,000 Black men in Tuskegee, Alabama, and selected for the study about 400 who were found to be infected with the sexually transmitted disease syphilis. The participants in the study were not informed that they were infected with syphilis or told about the expected outcomes of the experiment. Lindsay hoped to inspire Black people and other minorities who may be skeptical about the vaccine. After receiving the first of two doses, she said, “It feels surreal. It is a huge sense of relief for me, and hope.”

The first doses of the Pfizer vaccine to be given to Americans were shipped on Sunday, December 13. The United States is not the first country to approve the vaccine. On December 8, Margaret Keenan of the United Kingdom became the first person in the world to receive the authorized vaccine. Canada has also approved the vaccine, administering its first dose the same day as the United States.

In many cases, administration of a COVID-19 vaccine will be voluntary. But, it will be a while until everybody who wants a vaccine can get one. In the United States, the first doses will be given to health care workers. Frontline workers (workers likely to encounter the disease) and people who are vulnerable to the virus, including the elderly and people with such risk factors as obesity or diabetes will be next. Some of these people may receive the vaccine by the end of 2020. But, most people will have to wait until the spring of 2021.

Most vaccines are administered into the body by injection. A vaccine contains substances that stimulate the body’s immune system to produce molecules called antibodies. The immune system uses antibodies to fight against germs that enter the body. Antibodies produced in response to a vaccine can protect a person who is exposed to the actual disease-causing organism. The process of protecting the body in this way is called immunization. Vaccines have been successful in fighting many other diseases, including chickenpox, meningitis, and yellow fever.

Pfizer and Moderna began clinical trials in July. During these trials, participants were given either the vaccine or a placebo. A placebo is a substance that contains no active ingredient. Comparing infection rates in subjects who received the placebo with those among subjects who got the vaccine can help determine if the vaccine is effective. In the Pfizer and Moderna clinical trials, half the participants were given a placebo of salt water, and half were given the vaccine. The researchers then waited to see who might get sick. The results were very promising—both vaccines were about 95 percent effective in preventing COVID-19. By contrast, commonly administered influenza vaccines (known as flu shots) are 40 percent to 60 percent effective.

In late November, the companies Pfizer and Moderna each applied for emergency approval from the FDA for their COVID-19 vaccines.  The two companies are among dozens of drugmakers that have worked tirelessly to develop a vaccine against the deadly virus.

Tags: coronavirus, COVID-19, sandra lindsay, tuskegee syphilis study, v-day, vaccine
Posted in Current Events, Disasters, Health, Medicine, Natural Disasters, Race Relations, Science, Technology | Comments Off

Vaccines Provide Hope in COVID-19 Fight

Thursday, December 3rd, 2020
Nurse administering a vaccination. Credit: © Shutterstock

Nurse administering a vaccination.
Credit: © Shutterstock

The coronavirus disease COVID-19 has killed more than 1 million people and infected more than 60 million people around the world. But, hope may be just around the corner, in the form of vaccines. Vaccines are special medicines that can help make a person immune to a particular disease. Vaccines have been successful in fighting many other diseases, including chickenpox, meningitis, and yellow fever.

In late November, the companies Pfizer and Moderna each applied for emergency approval from the United States Food and Drug Administration (FDA) for their COVID-19 vaccines.  The two companies are among dozens of drugmakers that have worked tirelessly to develop a vaccine against the deadly virus.

Most vaccines are administered into the body by injection. A vaccine contains substances that stimulate the body’s immune system to produce molecules called antibodies. The immune system uses antibodies to fight against germs that enter the body. Antibodies produced in response to a vaccine can protect a person who is exposed to the actual disease-causing organism. The process of protecting the body in this way is called immunization. 

Pfizer and Moderna began clinical trials in July. During these trials, participants were given either the vaccine or a placebo. A placebo is a substance that contains no active ingredient. Comparing infection rates in subjects who received the placebo with those among subjects who got the vaccine can help determine if the vaccine is effective. In the Pfizer and Moderna clinical trials, half the participants were given a placebo of salt water, and half were given the vaccine. The researchers then waited to see who might get sick. The results were very promising—both vaccines were about 95 percent effective in preventing COVID-19. By contrast, commonly administered influenza vaccines (known as flu shots) are 40 percent to 60 percent effective.

Vaccines are one of the most powerful tools in modern medicine. They have nearly or completely eliminated several diseases. For instance, Edward Jenner, a British physician, introduced vaccination in 1796 as a preventive measure against smallpox. By the late 1970′s, smallpox vaccination had wiped out the dreadful disease. In the United States and many other countries, disease has been greatly reduced by widespread childhood immunizations. In 1952, for example, more than 21,000 cases of the paralytic disease polio were reported in the United States. By the end of the 1900′s, fewer than 10 cases per year were reported. More than 95 percent of children in the United States receive all their recommended immunizations by the time they enter school.

In many cases, administration of a COVID-19 vaccine will be voluntary. But, it will be a while until everybody who wants a vaccine can get one. Once approved, the vaccine—from Pfizer, Moderna, or other companies—will likely first be available to health care workers, frontline workers (workers likely to encounter the disease), and people who are vulnerable to the virus, including the elderly and people with such risk factors as obesity or diabetes. Some of these people may receive the vaccine by the end of 2020. But, most people will have to wait until the spring of 2021.

Tags: coronavirus, COVID-19, edward jenner, immunization, pandemic, vaccine
Posted in Business & Industry, Current Events, Health, Medicine, Science, Technology | Comments Off

Have a Safe Thanksgiving!

Monday, November 23rd, 2020
Credit: © Drazen Zigic, Shutterstock

Credit: © Drazen Zigic, Shutterstock

Cans of cranberries are piled high on grocery store shelves. The smells of pumpkin, cinnamon, and nutmeg float through the house. The sound of snapping green beans fills the air. It’s nearly Thanksgiving Day in the United States, the day set aside each year for giving thanks and remembering the blessings of life. People may celebrate the day with family gatherings, feasting, and prayer. For many people, Thanksgiving calls forth memories of tables crowded with food, happy reunions, football games, and religious contemplation.

But Thanksgiving Day—like so many holidays in 2020—might look different than in years past. In many places, efforts are being made to prevent the spread of the pandemic (global outbreak) of COVID-19. Such methods often include social distancing, meant to limit contact among people and thus the spread of germs. The U.S. Centers for Disease Control (CDC) has even advised Americans to avoid Thanksgiving travel and gatherings with relatives outside their household. That means that people might not see loved ones in person or crowd holiday tables this Thanksgiving Day. But, limiting the spread of germs does not mean you can’t have a day of thanks—and delicious foods. Just as you follow a recipe for your favorite Thanksgiving dish, follow these recipes for a safer Thanksgiving Day.

Gathering with people in your household is the safest way to celebrate the holiday. But that doesn’t mean you can’t enjoy the company of friends and distant relatives. Plan a video chat to share details of your meal, catch up with loved ones, and talk about the things you are thankful for.

If you must visit friends or relatives, it may help to wash your hands or use hand sanitizer before and after greeting others. Food tastes better with clean hands anyway. You want delicious butter on your warm roll—not yucky germs! When not eating, it may help to wear a protective face mask. Plus, a face mask is a great way to hide yawning. (Roasted turkey, a popular holiday dish, has a chemical called tryptophan that is said to cause drowsiness.)

One way to practice social distancing at a holiday gathering is to seat one household per table. This means that you can sit with anyone who lives in your house. So, your seatmates might include your parents, brothers and sisters, and any grandparents, aunts, uncles, and cousins that live in your home. Then, seat people from other households about 10 feet (3 meters) away. Before sitting down, disinfect your table and chairs. To pour on some additional safety—like you might pour on the gravy—bring your own drinks, plates, cups, and utensils.

We at World Book are thankful for our readers. We are also thankful to all the doctors, nurses, delivery drivers, and grocery store workers working to keep us safe and healthy. However you choose to celebrate, we hope you have a safe and fun Thanksgiving!

Tags: coronavirus, COVID-19, social distancing, thanksgiving
Posted in Current Events, Health, Holidays/Celebrations, Medicine | Comments Off

NBA Plays Again—at Disney World!

Tuesday, August 4th, 2020
T. J. Warren of the Indiana Pacers goes for a lay-up shot against the Philadelphia 76ers on August 1, 2020, at ESPN's Wide World of Sports at Disney World in Orlando, Florida. The NBA resumed its suspended 2019-2020 season with teams sequestered (isolated) at the resort and no fans in attendance, precautions against the spread of the COVID-19 pandemic (worldwide outbreak of disease). Virtual fans can be seen in the background, projected against the walls of the arena. Credit: © Jesse D. Garrabrant, NBAE/Getty Images

T. J. Warren of the Indiana Pacers goes for a lay-up shot against the Philadelphia 76ers on August 1, 2020, at ESPN’s Wide World of Sports at Disney World in Orlando, Florida. The NBA resumed its suspended 2019-2020 season with teams sequestered (isolated) at the resort and no fans in attendance, precautions against the spread of the COVID-19 pandemic (worldwide outbreak of disease). Virtual fans can be seen in the background, projected against the walls of the arena.
Credit: © Jesse D. Garrabrant, NBAE/Getty Images

The National Basketball Association (NBA) resumed its season on Thursday, July 30. But, this season looks much different than seasons past. Gone are the cheering fans. Instead, the stands are empty.

In March 2020, the NBA suspended its 2019-2020 season because of the ongoing COVID-19 pandemic. COVID-19, a contagious respiratory disease, first broke out in China in late 2019. It soon spread throughout the world. The NBA suspended play on March 11, 2020, after a Utah Jazz player tested positive for the disease. Most other major sports leagues around the world quickly followed the NBA in suspending or canceling scheduled events. In June, NBA teams and players agreed to a plan in which the top 22 teams in the standings would resume play under a shortened schedule to compete for a place in the playoffs.

All 22 teams are sequestered (isolated) at ESPN Wide World of Sports Complex and Walt Disney World Resort in Orlando, Florida. Living in this “bubble” is intended to protect the players, coaches, and staff from contracting and spreading COVID-19. The complex includes weight rooms, practice gyms, and game courts. There are no Disney princesses or pirates. But, there are many famous faces, including such top players as LeBron James and Zion Williamson.

The season resumed with a game between the Utah Jazz and the New Orleans Pelicans. The Jazz beat the Pelicans 106 to 104. That same night, the Los Angeles Clippers played the Los Angeles Lakers. It was another two-point victory—the Lakers beat the Clippers 103 to 101.

Opening night provided a platform for players and others to express support for Black Lives Matter (BLM). BLM is an activist movement that was formed to campaign against racial injustice and what its members consider police brutality against African Americans. BLACK LIVES MATTER was painted on the court, and the players knelt during the national anthem, an expression of protest begun by the American quarterback Colin Kaepernick.

The NBA is not the only sports league to resume suspended play. The National Hockey League (NHL) and Major League Baseball (MLB) have resumed their seasons, too. One thing all the leagues have in common is the absence of spectators at games. But at-home celebrations are likely to be spirited, as fans throughout the world have been without professional sports for months.

Tags: basketball, COVID-19, disney world, national basketball association, pandemic, social distancing
Posted in Current Events, Medicine, Recreation & Sports | Comments Off

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